Creating a dynamic GRN model - Questions (1)

• Aim:

  • Model as “realistic” as possible? Computational tool? Control network?

• GRN constituents

  • Genes (if so: what do they represent)? Transcription factors? Other regulators (e.g. regulatory RNA)? Intermediates (e.g. mRNA)? Signals?

• Processes to incorporate

  • Transcription? Translation? Breakdown? Signalling?

• Multicellularity

Notes: